Biochem/physiol Actions
Cell permeable: no
Reversible: no
Product does not compete with ATP.
Primary TargetPolymorphonuclear leukocytes
General description
Potent inflammatory agent, primarily because of its actions on polymorphonuclear leukocytes that include chemotaxis, aggregation, degranulation, and stimulation of adherence to vascular endothelium. Stimulates c-fos and c-jun proto-oncogene transcription in human monocytes. Involved in the pathogenesis of postischemic cerebral edema.
Potent proinflammatory agent, primarily because of its actions on polymorphonuclear leukocytes that include chemotaxis, aggregation, degranulation, and stimulation of adherence to vascular endothelium. Stimulates c-fos and c-jun proto-oncogene transcription in human monocytes. Involved in the pathogenesis of postischemic cerebral edema and asthma.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Other Notes
Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Kendall, A.P., et al. 1995. Anesthesia 50, 590.Dokter, W.H., et al. 1994. Leukemia 8, 1181.Jedlitschky, G., et al. 1991. J. Biol. Chem.266, 24763.
Packaging
50 µg in Alu drum
Physical form
In Ethanol.
Reconstitution
Following initial thaw, aliquot and freeze (-70°C).
Warning
Toxicity: Flammable (J)
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